Hearthpwn

"SavE THe 🅱EsT FoR lAST"
~  smol metal boi "Rise of Shadows"

"This place is scary!" followed by "*Lazer noises*"
~ Shaggy accompanied by Scoobs on steroids. "Saviors of Uldum"

"We must band together united for Dalaran!"
~ Chadgar "Rise of Shadows"

"You're up to no good? Me too!"
~Harry Potter and Dora The explorer fan "Rise of Shadows"

Well, I'm pretty satisfied with my openings, I opened 88 packs and I got:
323 Commons (Five of them were golden)

95 Rares (Also Five golden ones)

18 Epics (No golden)

And 4 leggys, one of them was golden:

Armagedillo

Hack the System

Zephrys the Great <---- Golden

Raid the Sky Temple

Aswell as Rogue quest as a login reward (Bazaar Burglary) and one guaranteed golden leggy from buying the 80 packs preorder Colossus of the Moon

Well, it's either keep your board relatively small and kill most of her wisps, or make a huge board and kill everything she puts on the battlefield with your weaker minions (if one of them dies, replace them with another big/small minion, depending on which one died), while going face with bigger ones. It's also a good idea to keep in mind while building your deck, to have at least 2 strong removals, if she is one of the last bosses. She only runs 2 copies of her bs card. Also, if you know or suspect that her secret is a Competitive Spirit, consider leaving only one minion on her side of the board, so she will not get the value out of it.

Good board clears are
Toki: Flamestrike/Blizzard/Arcane Explosion+spell damage

Darius Crowley: Brawl/Warpath (He also benefits from additional canons)

Shaw: Well, not quite many board clear options, but once she take control of your stronger minions, there is a decent chance that they were hurt, so King Mosh would be nice, plus I would suggest to take few copies (2 to 3) of Unleash the Hounds and something like Timber Wolf or Dire Wolf Alpha, since not only they shine especially in fight against her, but also are pretty good in other encounters.

Tess Greymane: Vanish, Fan of Knives, Cheap Shot, Blade Flurry

Of course, these are just suggestions, not a pro, just a decent player, who enjoys adventures, but hopefully this will make your runs less stressfull :).