DISENCHANT ALL OF THEM. If you end up needing them you can craft it for the same amount of dust you got for destroying them. There is absolutely no risk whatsoever to doing this, so don't bother asking about it just do it. Listen to Shia and JUST, DO IT! If it turns out you need that card for a deck you want to play, then just craft it back with no penalty (or don't dust it if you obviously need it) and there ya go. No thinking required, dust away.
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I'm here to kick ass and play cards, and I'm all out of ass.