Hearthpwn

I need to craft some new cards from the KC and here are some of the cards I'm ready to dust but as always I'm scared I will regret it. 

Legendaries: Madam Goya, Sergeant Sally, Blood Queen Lana'thel (I don't have the Lakkari Sacrifice and not planning to craft it), Moorabi, Tyrantus.

Epics: Fatespinner, Drakkari Enchanter....What other epics are safe to dust?

Drakkari Enchanter is good, I'd keep that.

I'd probably dust all those legendaries other than tyrantus maybe. I dust a lot of stuff though to build stuff I want.

I'd have personally kept queen as well as I p;lay a lot of warlock, but that's just me... dust everything (y)

All of the legendaries seem to be a rather safe DE. If you don't play wild I would start with the ones which will be rotated out (i.e. Goya and Sally). Out of the ones you mentioned which stay in the standard after the rotation I'd start with Blood-Queen if indeed you're sure you're not going to play Discardlock ever. Then Moorabi, and finally Tyrantus. The last one I'd try to keep as it is nice in Big Druid and also Quest Druid. It's not an amazing card by any means but it's fun and might somehow pan out. Moorabi is utter crap and I don't think Freeze Shaman will ever be a thing, but hey, it has tons of time left in standard so if you can afford keeping it, I'd also not rush into DE'ing it. 
Definitely don't DE Drakkari Enchanter. It is already played with Master Oakheart and has a potentially really strong effect, that might be supported further in later expansions. Fatespinner seems like a safe DE.

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